Navigating the expansive frontier of Red Dead Redemption 2 requires players to stay vigilant against hostile factions scattered across the map. To achieve full completion in the game's compendium, you must track down and interact with six primary rival gangs. Each group controls specific territories, operating out of unique hideouts and setup camps that reflect their lore.

The Northern Threat: O'Driscoll Boys and Murfree Brood

The O'Driscoll Boys represent one of the most prominent factions encountered early in Arthur Morgan's journey. They frequently roam the grasslands of New Hanover and northern West Elizabeth, operating hideouts at Six Point Cabin and Hanging Dog Ranch. Eliminating their outposts is essential for clearing out early-game hostile territories.

Further to the east, the terrifying Murfree Brood inhabits the dense, rugged woods of Roanoke Ridge in northeastern New Hanover. Known for their brutal tactics and isolated lifestyle, their primary stronghold is hidden deep inside Beaver Hollow. Exploring these dark forest trails often results in sudden ambushes from this savage group.

Southern Hostilities: Lemoyne Raiders and Del Lobo Gang

In the southern territory of Lemoyne, former Confederate soldiers form the aggressive Lemoyne Raiders. They dominate central Lemoyne and Scarlett Meadows, establishing their main hideout at the historic Shady Belle estate. Players traveling near Rhodes must remain cautious to avoid their heavily armed patrols.

Farther west in the arid landscapes of New Austin lies the turf of the ruthless Del Lobo Gang. This faction holds multiple operational strongholds including Fort Mercer, Thieves Landing, Twin Rocks, and Solomon's Folly. Tracking them down allows players to explore the western frontier while completing late-game challenges.

The Epilogue Factions: Skinner Brothers and Laramie Gang

The Skinner Brothers are a nomadic and violent faction residing in the wilderness of Tall Trees within West Elizabeth. Unlike other groups, they lack a single permanent hideout and instead rely on unpredictable wilderness camps and guerilla ambushes. Facing them requires careful planning due to their silent and deadly weapon choices.

Finally, the Laramie Gang emerges primarily during the epilogue chapters as mercenary enforcers operating in northern West Elizabeth. They frequently clash with local ranchers near Big Valley and the areas surrounding Strawberry. Finding their patrols offers unique combat encounters as you finalize your regional exploration.

Tips for Clearing Gang Hideouts and Completing the Compendium

Infiltrating a gang hideout successfully demands tactical positioning and adequate weapon preparation. Approach enemy encampments quietly to evaluate sentry positions before launching a full assault. Utilizing Dead Eye effectively ensures you can eliminate high-priority targets before getting overwhelmed by reinforcements.

Clearing these outposts not only advances your compendium stats but also yields valuable loot like cash, jewelry, and rare weapons. Defeating all six compendium gangs grants players a comprehensive understanding of the game's rich world and unlocks essential completion achievements.